mTOR is required for pulmonary arterial vascular smooth muscle cell proliferation under chronic hypoxia

Pulmonary arterial vascular smooth muscle (PAVSM) cell proliferation is a key pathophysiological component of vascular remodeling in pulmonary arterial hypertension (PAH) for which cellular and molecular mechanisms are poorly understood. The goal of our study was to determine the role of mammalian t...

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Bibliografiska uppgifter
Huvudupphovsmän: Krymskaya, Vera P., Snow, Jennifer, Cesarone, Gregory, Khavin, Irene, Goncharov, Dmitry A., Lim, Poay N., Veasey, Sigrid C., Ihida-Stansbury, Kaori, Jones, Peter L., Goncharova, Elena A.
Materialtyp: Artigo
Språk:Inglês
Publicerad: Federation of American Societies for Experimental Biology 2011
Ämnen:
Research Communications
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3101038/
https://ncbi.nlm.nih.gov/pubmed/21368105
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1096/fj.10-175018
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