Nuclear Receptor-Like Structure and Interaction of Congenital Heart Disease-Associated Factors GATA4 and NKX2-5

AIMS: Transcription factor GATA4 is a dosage sensitive regulator of heart development and alterations in its level or activity lead to congenital heart disease (CHD). GATA4 has also been implicated in cardiac regeneration and repair. GATA4 action involves combinatorial interaction with other cofacto...

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Bibliografske podrobnosti
izdano v:PLoS One
Main Authors: Kinnunen, Sini, Välimäki, Mika, Tölli, Marja, Wohlfahrt, Gerd, Darwich, Rami, Komati, Hiba, Nemer, Mona, Ruskoaho, Heikki
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science 2015
Teme:
Research Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4671672/
https://ncbi.nlm.nih.gov/pubmed/26642209
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0144145
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