GATA-targeted compounds modulate cardiac subtype cell differentiation in dual reporter stem cell line

BACKGROUND: Pharmacological modulation of cell fate decisions and developmental gene regulatory networks holds promise for the treatment of heart failure. Compounds that target tissue-specific transcription factors could overcome non-specific effects of small molecules and lead to the regeneration o...

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Bibliographic Details
Published in:Stem Cell Res Ther
Main Authors: Välimäki, Mika J., Leigh, Robert S., Kinnunen, Sini M., March, Alexander R., de Sande, Ana Hernández, Kinnunen, Matias, Varjosalo, Markku, Heinäniemi, Merja, Kaynak, Bogac L., Ruskoaho, Heikki
Format: Artigo
Language:Inglês
Published: BioMed Central 2021
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Research
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7977156/
https://ncbi.nlm.nih.gov/pubmed/33736688
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13287-021-02259-z
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