Structure and activity of the Saccharomyces cerevisiae dUTP pyrophosphatase DUT1, an essential housekeeping enzyme

Genomes of all free-living organisms encode the enzyme dUTPase (dUTP pyrophosphatase), which plays a key role in preventing uracil incorporation into DNA. In the present paper, we describe the biochemical and structural characterization of DUT1 (Saccharomyces cerevisiae dUTPase). The hydrolysis of d...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Biochem J
Egile Nagusiak: Tchigvintsev, Anatoli, Singer, Alexander U., Flick, Robert, Petit, Pierre, Brown, Greg, Evdokimova, Elena, Savchenko, Alexei, Yakunin, Alexander F.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2011
Gaiak:
Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC4671291/
https://ncbi.nlm.nih.gov/pubmed/21548881
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20110304
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