Enhanced Detection of Antigen-Specific CD4(+) T Cells Using Altered Peptide Flanking Residue Peptide–MHC Class II Multimers

Fluorochrome-conjugated peptide–MHC (pMHC) class I multimers are staple components of the immunologist’s toolbox, enabling reliable quantification and analysis of Ag-specific CD8(+) T cells irrespective of functional outputs. In contrast, widespread use of the equivalent pMHC class II (pMHC-II) reag...

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Detalhes bibliográficos
Publicado no:J Immunol
Main Authors: Holland, Christopher J., Dolton, Garry, Scurr, Martin, Ladell, Kristin, Schauenburg, Andrea J., Miners, Kelly, Madura, Florian, Sewell, Andrew K., Price, David A., Cole, David K., Godkin, Andrew J.
Formato: Artigo
Idioma:Inglês
Publicado em: AAI 2015
Assuntos:
Novel Immunological Methods
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4671089/
https://ncbi.nlm.nih.gov/pubmed/26553072
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1402787
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