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Structural basis for ineffective T-cell responses to MHC anchor residue-improved “heteroclitic” peptides
MHC anchor residue-modified “heteroclitic” peptides have been used in many cancer vaccine trials and often induce greater immune responses than the wild-type peptide. The best-studied system to date is the decamer MART-1/Melan-A(26–35) peptide, EAAGIGILTV, where the natural alanine at position 2 has...
Tallennettuna:
| Julkaisussa: | Eur J Immunol |
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| Päätekijät: | , , , , , , , , |
| Aineistotyyppi: | Artigo |
| Kieli: | Inglês |
| Julkaistu: |
BlackWell Publishing Ltd
2015
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| Aiheet: | |
| Linkit: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4357396/ https://ncbi.nlm.nih.gov/pubmed/25471691 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/eji.201445114 |
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