TCR‐induced alteration of primary MHC peptide anchor residue

The HLA‐A*02:01‐restricted decapeptide EAAGIGILTV, derived from melanoma antigen recognized by T‐cells‐1 (MART‐1) protein, represents one of the best‐studied tumor associated T‐cell epitopes, but clinical results targeting this peptide have been disappointing. This limitation may reflect the dominan...

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Dettagli Bibliografici
Pubblicato in:Eur J Immunol
Autori principali: Madura, Florian, Rizkallah, Pierre J., Legut, Mateusz, Holland, Christopher J., Fuller, Anna, Bulek, Anna, Schauenburg, Andrea J., Trimby, Andrew, Hopkins, Jade R., Wells, Stephen A., Godkin, Andrew, Miles, John J., Sami, Malkit, Li, Yi, Liddy, Nathaniel, Jakobsen, Bent K., Loveridge, E. Joel, Cole, David K., Sewell, Andrew K.
Natura: Artigo
Lingua:Inglês
Pubblicazione: John Wiley and Sons Inc. 2019
Soggetti:
Molecular immunology and signaling
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6618058/
https://ncbi.nlm.nih.gov/pubmed/31091334
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/eji.201948085
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