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RNA editing by ADAR1 marks dsRNA as “self”
A paper recently published in Science reports that adenosine deaminase acting on RNA 1-dependent adenosine-to-inosine editing marks endogenous double strand RNA as self and prevents their immune recognition by cytosolic RNA sensor MDA5.
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| Veröffentlicht in: | Cell Res |
|---|---|
| Hauptverfasser: | , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Nature Publishing Group
2015
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4670992/ https://ncbi.nlm.nih.gov/pubmed/26596786 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cr.2015.135 |
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