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Tumor-Unrelated CD4 T Cell Help Augments CD134 plus CD137 Dual Costimulation Tumor Therapy
The ability of immune-based cancer therapies to elicit beneficial CD8(+) CTL is limited by tolerance pathways that inactivate tumor-specific CD4 helper T cells. A strategy to bypass this problem is to engage tumor-unrelated CD4 helper T cells. Thus, CD4 T cells, regardless of their specificity per s...
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| Pubblicato in: | J Immunol |
|---|---|
| Autori principali: | , , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2015
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4670784/ https://ncbi.nlm.nih.gov/pubmed/26561553 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1502032 |
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