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Betting on improved cancer immunotherapy by doubling down on CD134 and CD137 co-stimulation
The ability of T cells to recognize a vast array of antigens enables them to destroy tumor cells while inflicting minimal collateral damage. Nevertheless, tumor antigens often are a form of self-antigen, and thus tumor immunity can be dampened by tolerance mechanisms that evolved to prevent autoimmu...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Landes Bioscience
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3583935/ https://ncbi.nlm.nih.gov/pubmed/23482891 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/onci.22837 |
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