CD134 Plus CD137 Dual Costimulation Induces Eomesodermin in CD4 T Cells to Program Cytotoxic Th1 Differentiation

Cytotoxic CD4 Th1 cells are emerging as a therapeutically useful T cell lineage that can effectively target tumors, but until now the pathways that govern their differentiation have been poorly understood. We demonstrate that CD134 (OX40) costimulation programs naive self- and virus-reactive CD4 T c...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Hauptverfasser: Qui, Harry Z., Hagymasi, Adam T., Bandyopadhyay, Suman, St. Rose, Marie-Clare, Ramanarasimhaiah, Raghunath, Ménoret, Antoine, Mittler, Robert S., Gordon, Scott M., Reiner, Steven L., Vella, Anthony T., Adler, Adam J.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2011
Schlagworte:
Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3178659/
https://ncbi.nlm.nih.gov/pubmed/21880986
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1101244
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!

Ähnliche Einträge