Načítá se...

The Role of Aggregates of Therapeutic Protein Products in Immunogenicity: An Evaluation by Mathematical Modeling

Therapeutic protein products (TPP) have been widely used to treat a variety of human diseases, including cancer, hemophilia, and autoimmune diseases. However, TPP can induce unwanted immune responses that can impact both drug efficacy and patient safety. The presence of aggregates is of particular c...

Celý popis

Uloženo v:
Podrobná bibliografie
Vydáno v:J Immunol Res
Hlavní autoři: Yin, Liusong, Chen, Xiaoying, Tiwari, Abhinav, Vicini, Paolo, Hickling, Timothy P.
Médium: Artigo
Jazyk:Inglês
Vydáno: Hindawi Publishing Corporation 2015
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4670651/
https://ncbi.nlm.nih.gov/pubmed/26682236
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2015/401956
Tagy: Přidat tag
Žádné tagy, Buďte první, kdo otaguje tento záznam!