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Immunogenicity of Bioproducts: Cellular Models to Evaluate the Impact of Therapeutic Antibody Aggregates

Patients treated with bioproducts (BPs) frequently develop anti-drug antibodies (ADAs) with potential neutralizing capacities leading to loss of clinical response or potential hypersensitivity reactions. Many factors can influence BP immunogenicity and could be related to the patient, the treatment,...

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Сохранить в:
Библиографические подробности
Опубликовано в: :Front Immunol
Главные авторы: Nabhan, Myriam, Pallardy, Marc, Turbica, Isabelle
Формат: Artigo
Язык:Inglês
Опубликовано: Frontiers Media S.A. 2020
Предметы:
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC7214678/
https://ncbi.nlm.nih.gov/pubmed/32431697
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2020.00725
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