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Dissecting seipin function: the localized accumulation of phosphatidic acid at ER/LD junctions in the absence of seipin is suppressed by Sei1p(ΔNterm) only in combination with Ldb16p

BACKGROUND: Seipin is required for the correct assembly of cytoplasmic lipid droplets. In the absence of the yeast seipin homolog Sei1p (formerly Fld1p), droplets are slow to bud from the endoplasmic reticulum, lack the normal component of proteins on their surface, are highly heterogeneous in size...

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Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:BMC Cell Biol
Egile Nagusiak: Han, Sungwon, Binns, Derk D., Chang, Yu-Fang, Goodman, Joel M.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: BioMed Central 2015
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC4670494/
https://ncbi.nlm.nih.gov/pubmed/26637296
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12860-015-0075-3
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