Seipin negatively regulates sphingolipid production at the ER–LD contact site

Seipin is known for its critical role in controlling lipid droplet (LD) assembly at the LD-forming subdomain of the endoplasmic reticulum (ER). Here, we identified a new function of seipin as a negative regulator for sphingolipid production. We show that yeast cells lacking seipin displayed altered...

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Detalhes bibliográficos
Publicado no:J Cell Biol
Main Authors: Su, Wei-Cheng, Lin, Yi-Hsiu, Pagac, Martin, Wang, Chao-Wen
Formato: Artigo
Idioma:Inglês
Publicado em: Rockefeller University Press 2019
Assuntos:
Research Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6829658/
https://ncbi.nlm.nih.gov/pubmed/31594806
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201902072
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