Genomic Profiling Reveals Unique Molecular Alterations in Hepatoblastomas and Adjacent Hepatocellular Carcinomas in B6C3F1 Mice

The cell of origin of hepatoblastoma in humans and mice is unknown; it is hypothesized to be a transformed hepatocyte, oval cell, or hepatic progenitor cell. In mice, current dogma is that hepatoblastomas arise from pre-existing hepatocellular neoplasms as a result of further neoplastic transformati...

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Udgivet i:Toxicol Pathol
Main Authors: Bhusari, Sachin, Pandiri, Arun R., Nagai, Hiroaki, Wang, Yu, Foley, Julie, Hong, Hue-Hua L., Ton, Thai-Vu, DeVito, Michael, Shockley, Keith R., Peddada, Shyamal D., Gerrish, Kevin E., Malarkey, David E., Hooth, Michelle J., Sills, Robert C., Hoenerhoff, Mark J.
Format: Artigo
Sprog:Inglês
Udgivet: 2015
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4670276/
https://ncbi.nlm.nih.gov/pubmed/26289556
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/0192623315599853
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