Hrd1 and ER-Associated Protein Degradation, ERAD, Are Critical Elements of the Adaptive ER Stress Response in Cardiac Myocytes

RATIONALE: Hrd1 is an endoplasmic reticulum (ER)-transmembrane E3 ubiquitin ligase that has been studied in yeast, where it contributes to ER protein quality control by ER-associated degradation (ERAD) of misfolded proteins that accumulate during ER stress. Neither Hrd1 nor ERAD have been studied in...

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Détails bibliographiques
Publié dans:Circ Res
Auteurs principaux: Doroudgar, Shirin, Völkers, Mirko, Thuerauf, Donna J, Khan, Mohsin, Mohsin, Sadia, Respress, Jonathan L, Wang, Wei, Gude, Natalie, Müller, Oliver J, Wehrens, Xander HT, Sussman, Mark A, Glembotski, Christopher C
Format: Artigo
Langue:Inglês
Publié: 2015
Sujets:
Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4670262/
https://ncbi.nlm.nih.gov/pubmed/26137860
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/CIRCRESAHA.115.306993
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