Phosphorylation of Sterol Regulatory Element Binding Protein-1a by Protein Kinase A (PKA) Regulates Transcriptional Activity

The counter-regulatory hormone glucagon inhibits lipogenesis via downregulation of sterol regulatory element binding protein 1 (SREBP-1). The effect of glucagon is mediated via protein kinase A (PKA). To determine if SREBP-1 is a direct phosphorylation target of PKA, we conducted mass spectrometry a...

Descrizione completa

Salvato in:
Dettagli Bibliografici
Pubblicato in:Biochem Biophys Res Commun
Autori principali: Dong, Qingming, Giorgianni, Francesco, Deng, Xiong, Beranova-Giorgianni, Sarka, Bridges, Dave, Park, Edwards A., Raghow, Rajendra, Elam, Marshall B.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2014
Soggetti:
Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4670028/
https://ncbi.nlm.nih.gov/pubmed/24853806
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbrc.2014.05.046
Tags: Aggiungi Tag
Nessun Tag, puoi essere il primo ad aggiungerne! !

Documenti analoghi