Phosphorylation of Sterol Regulatory Element Binding Protein-1a by Protein Kinase A (PKA) Regulates Transcriptional Activity

The counter-regulatory hormone glucagon inhibits lipogenesis via downregulation of sterol regulatory element binding protein 1 (SREBP-1). The effect of glucagon is mediated via protein kinase A (PKA). To determine if SREBP-1 is a direct phosphorylation target of PKA, we conducted mass spectrometry a...

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Detalhes bibliográficos
Publicado no:Biochem Biophys Res Commun
Main Authors: Dong, Qingming, Giorgianni, Francesco, Deng, Xiong, Beranova-Giorgianni, Sarka, Bridges, Dave, Park, Edwards A., Raghow, Rajendra, Elam, Marshall B.
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4670028/
https://ncbi.nlm.nih.gov/pubmed/24853806
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbrc.2014.05.046
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