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Insulin activates the rat sterol-regulatory-element-binding protein 1c (SREBP-1c) promoter through the combinatorial actions of SREBP, LXR, Sp-1 and NF-Y cis-acting elements

The enhanced synthesis of fatty acids in the liver and adipose tissue in response to insulin is critically dependent on the transcription factor SREBP-1c (sterol-regulatory-element-binding protein 1c). Insulin increases the expression of the SREBP-1c gene in intact liver and in hepatocytes cultured...

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Bibliografske podrobnosti
Main Authors: Cagen, Lauren M., Deng, Xiong, Wilcox, Henry G., Park, Edwards A., Raghow, Rajendra, Elam, Marshall B.
Format: Artigo
Jezik:Inglês
Izdano: Portland Press Ltd. 2004
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC1134689/
https://ncbi.nlm.nih.gov/pubmed/15330762
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20040162
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