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ALTernative Telomere Maintenance and Cancer
Activation of a telomere maintenance mechanism (TMM) is permissive for replicative immortality and a hallmark of human cancer. While most cancers rely on reactivation of telomerase, a significant fraction utilizes the recombination dependent alternative lengthening of telomeres (ALT) pathway. ALT is...
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| Pubblicato in: | Trends Cancer |
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| Autori principali: | , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2015
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4669901/ https://ncbi.nlm.nih.gov/pubmed/26645051 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.trecan.2015.07.007 |
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