RGD-modifided oncolytic adenovirus exhibited potent cytotoxic effect on CAR-negative bladder cancer-initiating cells

Cancer-initiating cell (CIC) is critical in cancer development, maintenance and recurrence. The reverse expression pattern of coxsackie and adenovirus receptor (CAR) and α(ν) integrin in bladder cancer decreases the infection efficiency of adenovirus. We constructed Arg-Gly-Asp (RGD)-modified oncoly...

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Salvato in:
Dettagli Bibliografici
Pubblicato in:Cell Death Dis
Autori principali: Yang, Y, Xu, H, Shen, J, Wu, S, Xiao, J, Xu, Y, Liu, X-Y, Chu, L
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group 2015
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Original Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4669706/
https://ncbi.nlm.nih.gov/pubmed/25973680
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cddis.2015.128
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