RGD-modifided oncolytic adenovirus exhibited potent cytotoxic effect on CAR-negative bladder cancer-initiating cells

Cancer-initiating cell (CIC) is critical in cancer development, maintenance and recurrence. The reverse expression pattern of coxsackie and adenovirus receptor (CAR) and α(ν) integrin in bladder cancer decreases the infection efficiency of adenovirus. We constructed Arg-Gly-Asp (RGD)-modified oncoly...

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Detalles Bibliográficos
Publicado en:Cell Death Dis
Main Authors: Yang, Y, Xu, H, Shen, J, Wu, S, Xiao, J, Xu, Y, Liu, X-Y, Chu, L
Formato: Artigo
Idioma:Inglês
Publicado: Nature Publishing Group 2015
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Original Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4669706/
https://ncbi.nlm.nih.gov/pubmed/25973680
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cddis.2015.128
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