RGD-modifided oncolytic adenovirus exhibited potent cytotoxic effect on CAR-negative bladder cancer-initiating cells

Cancer-initiating cell (CIC) is critical in cancer development, maintenance and recurrence. The reverse expression pattern of coxsackie and adenovirus receptor (CAR) and α(ν) integrin in bladder cancer decreases the infection efficiency of adenovirus. We constructed Arg-Gly-Asp (RGD)-modified oncoly...

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Bibliografische gegevens
Gepubliceerd in:Cell Death Dis
Hoofdauteurs: Yang, Y, Xu, H, Shen, J, Wu, S, Xiao, J, Xu, Y, Liu, X-Y, Chu, L
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Nature Publishing Group 2015
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Original Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4669706/
https://ncbi.nlm.nih.gov/pubmed/25973680
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cddis.2015.128
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