The Role of ARX in Human Pancreatic Endocrine Specification

The in vitro differentiation of human embryonic stem cells (hESCs) offers a model system to explore human development. Humans with mutations in the transcription factor Aristaless Related Homeobox (ARX) often suffer from the syndrome X-linked lissencephaly with ambiguous genitalia (XLAG), affecting...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Gage, Blair K., Asadi, Ali, Baker, Robert K., Webber, Travis D., Wang, Rennian, Itoh, Masayuki, Hayashi, Masaharu, Miyata, Rie, Akashi, Takumi, Kieffer, Timothy J.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2015
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4669132/
https://ncbi.nlm.nih.gov/pubmed/26633894
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0144100
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