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Initial cell seeding density influences pancreatic endocrine development during in vitro differentiation of human embryonic stem cells.

Human embryonic stem cells (hESCs) have the ability to form cells derived from all three germ layers, and as such have received significant attention as a possible source for insulin-secreting pancreatic beta-cells for diabetes treatment. While considerable advances have been made in generating hESC...

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Detalhes bibliográficos
Main Authors: Blair K Gage, Travis D Webber, Timothy J Kieffer
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science (PLoS) 2013-01-01
Colecção:PLoS ONE
Acesso em linha:http://europepmc.org/articles/PMC3852888?pdf=render
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