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Nkx2.2 and Arx genetically interact to regulate pancreatic endocrine cell development and endocrine hormone expression
Nkx2.2 and Arx are essential pancreatic transcription factors. Nkx2.2 is necessary for the appropriate specification of the islet alpha, beta, PP and epsilon cell lineages, whereas Arx is required to form the correct ratio of alpha, beta, delta and PP cells. To begin to understand the cooperative fu...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3192309/ https://ncbi.nlm.nih.gov/pubmed/21856296 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ydbio.2011.08.001 |
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