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Nkx2.2 and Arx genetically interact to regulate pancreatic endocrine cell development and endocrine hormone expression

Nkx2.2 and Arx are essential pancreatic transcription factors. Nkx2.2 is necessary for the appropriate specification of the islet alpha, beta, PP and epsilon cell lineages, whereas Arx is required to form the correct ratio of alpha, beta, delta and PP cells. To begin to understand the cooperative fu...

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Bibliografski detalji
Glavni autori: Mastracci, Teresa L., Wilcox, Crystal, Panea, Casandra, Golden, Jeffery A., May, Catherine Lee, Sussel, Lori
Format: Artigo
Jezik:Inglês
Izdano: 2011
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3192309/
https://ncbi.nlm.nih.gov/pubmed/21856296
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ydbio.2011.08.001
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