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Minor Loops in Major Folds: Enhancer–Promoter Looping, Chromatin Restructuring, and Their Association with Transcriptional Regulation and Disease

The organization and folding of chromatin within the nucleus can determine the outcome of gene expression. Recent technological advancements have enabled us to study chromatin interactions in a genome-wide manner at high resolution. These studies have increased our understanding of the hierarchy and...

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Detalhes bibliográficos
Publicado no:PLoS Genet
Main Authors: Matharu, Navneet, Ahituv, Nadav
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4669122/
https://ncbi.nlm.nih.gov/pubmed/26632825
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1005640
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