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Chromatin Loops as Allosteric Modulators of Enhancer-Promoter Interactions
The classic model of eukaryotic gene expression requires direct spatial contact between a distal enhancer and a proximal promoter. Recent Chromosome Conformation Capture (3C) studies show that enhancers and promoters are embedded in a complex network of looping interactions. Here we use a polymer mo...
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| Hauptverfasser: | , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Public Library of Science
2014
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4207457/ https://ncbi.nlm.nih.gov/pubmed/25340767 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1003867 |
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