Retinoid X receptor activation reverses age-related deficiencies in myelin debris phagocytosis and remyelination

The efficiency of central nervous system remyelination declines with age. This is in part due to an age-associated decline in the phagocytic removal of myelin debris, which contains inhibitors of oligodendrocyte progenitor cell differentiation. In this study, we show that expression of genes involve...

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Опубликовано в: :Brain
Главные авторы: Natrajan, Muktha S., de la Fuente, Alerie G., Crawford, Abbe H., Linehan, Eimear, Nuñez, Vanessa, Johnson, Kory R., Wu, Tianxia, Fitzgerald, Denise C., Ricote, Mercedes, Bielekova, Bibiana, Franklin, Robin J. M.
Формат: Artigo
Язык:Inglês
Опубликовано: Oxford University Press 2015
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Original Articles
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC4668920/
https://ncbi.nlm.nih.gov/pubmed/26463675
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/brain/awv289
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