Retinoid X receptor activation reverses age-related deficiencies in myelin debris phagocytosis and remyelination

The efficiency of central nervous system remyelination declines with age. This is in part due to an age-associated decline in the phagocytic removal of myelin debris, which contains inhibitors of oligodendrocyte progenitor cell differentiation. In this study, we show that expression of genes involve...

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Detaylı Bibliyografya
Yayımlandı:Brain
Asıl Yazarlar: Natrajan, Muktha S., de la Fuente, Alerie G., Crawford, Abbe H., Linehan, Eimear, Nuñez, Vanessa, Johnson, Kory R., Wu, Tianxia, Fitzgerald, Denise C., Ricote, Mercedes, Bielekova, Bibiana, Franklin, Robin J. M.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Oxford University Press 2015
Konular:
Original Articles
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4668920/
https://ncbi.nlm.nih.gov/pubmed/26463675
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/brain/awv289
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