Retinoid X receptor activation reverses age-related deficiencies in myelin debris phagocytosis and remyelination

The efficiency of central nervous system remyelination declines with age. This is in part due to an age-associated decline in the phagocytic removal of myelin debris, which contains inhibitors of oligodendrocyte progenitor cell differentiation. In this study, we show that expression of genes involve...

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Detalhes bibliográficos
Publicado no:Brain
Main Authors: Natrajan, Muktha S., de la Fuente, Alerie G., Crawford, Abbe H., Linehan, Eimear, Nuñez, Vanessa, Johnson, Kory R., Wu, Tianxia, Fitzgerald, Denise C., Ricote, Mercedes, Bielekova, Bibiana, Franklin, Robin J. M.
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2015
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Original Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4668920/
https://ncbi.nlm.nih.gov/pubmed/26463675
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/brain/awv289
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