Retinoid X receptor activation reverses age-related deficiencies in myelin debris phagocytosis and remyelination

The efficiency of central nervous system remyelination declines with age. This is in part due to an age-associated decline in the phagocytic removal of myelin debris, which contains inhibitors of oligodendrocyte progenitor cell differentiation. In this study, we show that expression of genes involve...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Brain
Egile Nagusiak: Natrajan, Muktha S., de la Fuente, Alerie G., Crawford, Abbe H., Linehan, Eimear, Nuñez, Vanessa, Johnson, Kory R., Wu, Tianxia, Fitzgerald, Denise C., Ricote, Mercedes, Bielekova, Bibiana, Franklin, Robin J. M.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Oxford University Press 2015
Gaiak:
Original Articles
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC4668920/
https://ncbi.nlm.nih.gov/pubmed/26463675
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/brain/awv289
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