A genome-wide association study identifies risk loci for spirometric measures among smokers of European and African ancestry

BACKGROUND: Pulmonary function decline is a major contributor to morbidity and mortality among smokers. Post bronchodilator FEV(1) and FEV(1)/FVC ratio are considered the standard assessment of airflow obstruction. We performed a genome-wide association study (GWAS) in 9919 current and former smoker...

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Αποθηκεύτηκε σε:
Λεπτομέρειες βιβλιογραφικής εγγραφής
Τόπος έκδοσης:BMC Genet
Κύριοι συγγραφείς: Lutz, Sharon M., Cho, Michael H., Young, Kendra, Hersh, Craig P., Castaldi, Peter J., McDonald, Merry-Lynn, Regan, Elizabeth, Mattheisen, Manuel, DeMeo, Dawn L., Parker, Margaret, Foreman, Marilyn, Make, Barry J., Jensen, Robert L., Casaburi, Richard, Lomas, David A., Bhatt, Surya P., Bakke, Per, Gulsvik, Amund, Crapo, James D., Beaty, Terri H., Laird, Nan M., Lange, Christoph, Hokanson, John E., Silverman, Edwin K.
Μορφή: Artigo
Γλώσσα:Inglês
Έκδοση: BioMed Central 2015
Θέματα:
Research Article
Διαθέσιμο Online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4668640/
https://ncbi.nlm.nih.gov/pubmed/26634245
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12863-015-0299-4
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