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Genome-Wide Association Study of the Genetic Determinants of Emphysema Distribution

Rationale: Emphysema has considerable variability in the severity and distribution of parenchymal destruction throughout the lungs. Upper lobe–predominant emphysema has emerged as an important predictor of response to lung volume reduction surgery. Yet, aside from alpha-1 antitrypsin deficiency, the...

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Veröffentlicht in:Am J Respir Crit Care Med
Hauptverfasser: Boueiz, Adel, Lutz, Sharon M., Cho, Michael H., Hersh, Craig P., Bowler, Russell P., Washko, George R., Halper-Stromberg, Eitan, Bakke, Per, Gulsvik, Amund, Laird, Nan M., Beaty, Terri H., Coxson, Harvey O., Crapo, James D., Silverman, Edwin K., Castaldi, Peter J., DeMeo, Dawn L.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Thoracic Society 2017
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5363968/
https://ncbi.nlm.nih.gov/pubmed/27669027
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1164/rccm.201605-0997OC
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