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New Insight into Long-Range Nonadditivity within Protein Double-Mutant Cycles

Additivity principles in chemistry, biochemistry, and biophysics have been used extensively for decades. Nevertheless, it is well known that additivity frequently breaks down in complex biomacromolecules. Nonadditivity within protein double mutant free energy cycles of spatially close residue pairs...

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Bibliografiska uppgifter
I publikationen:Proteins
Huvudupphovsmän: Istomin, Andrei Y., Gromiha, M. Michael, Vorov, Oleg K., Jacobs, Donald J., Livesay, Dennis R.
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2008
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC4667956/
https://ncbi.nlm.nih.gov/pubmed/17803237
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/prot.21620
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