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New Insight into Long-Range Nonadditivity within Protein Double-Mutant Cycles
Additivity principles in chemistry, biochemistry, and biophysics have been used extensively for decades. Nevertheless, it is well known that additivity frequently breaks down in complex biomacromolecules. Nonadditivity within protein double mutant free energy cycles of spatially close residue pairs...
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| Publicado no: | Proteins |
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| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4667956/ https://ncbi.nlm.nih.gov/pubmed/17803237 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/prot.21620 |
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