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New Insight into Long-Range Nonadditivity within Protein Double-Mutant Cycles

Additivity principles in chemistry, biochemistry, and biophysics have been used extensively for decades. Nevertheless, it is well known that additivity frequently breaks down in complex biomacromolecules. Nonadditivity within protein double mutant free energy cycles of spatially close residue pairs...

詳細記述

保存先:
書誌詳細
出版年:Proteins
主要な著者: Istomin, Andrei Y., Gromiha, M. Michael, Vorov, Oleg K., Jacobs, Donald J., Livesay, Dennis R.
フォーマット: Artigo
言語:Inglês
出版事項: 2008
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC4667956/
https://ncbi.nlm.nih.gov/pubmed/17803237
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/prot.21620
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