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New Insight into Long-Range Nonadditivity within Protein Double-Mutant Cycles

Additivity principles in chemistry, biochemistry, and biophysics have been used extensively for decades. Nevertheless, it is well known that additivity frequently breaks down in complex biomacromolecules. Nonadditivity within protein double mutant free energy cycles of spatially close residue pairs...

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Bibliografische gegevens
Gepubliceerd in:Proteins
Hoofdauteurs: Istomin, Andrei Y., Gromiha, M. Michael, Vorov, Oleg K., Jacobs, Donald J., Livesay, Dennis R.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2008
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4667956/
https://ncbi.nlm.nih.gov/pubmed/17803237
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/prot.21620
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