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Valproic Acid Use During Radiation Therapy for Glioblastoma Associated With Improved Survival

PURPOSE: Valproic acid (VA) is an antiepileptic drug (AED) and histone deacetylase (HDAC) inhibitor taken by patients with glioblastoma (GB) to manage seizures, and it can modulate the biologic effects of radiation therapy (RT). We investigated whether VA use during RT for GB was associated with ove...

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Detalhes bibliográficos
Publicado no:Int J Radiat Oncol Biol Phys
Main Authors: Barker, Christopher A., Bishop, Andrew J., Chang, Maria, Beal, Kathryn, Chan, Timothy A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4667941/
https://ncbi.nlm.nih.gov/pubmed/23523186
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ijrobp.2013.02.012
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