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Valproic Acid Use During Radiation Therapy for Glioblastoma Associated With Improved Survival

PURPOSE: Valproic acid (VA) is an antiepileptic drug (AED) and histone deacetylase (HDAC) inhibitor taken by patients with glioblastoma (GB) to manage seizures, and it can modulate the biologic effects of radiation therapy (RT). We investigated whether VA use during RT for GB was associated with ove...

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Pubblicato in:Int J Radiat Oncol Biol Phys
Autori principali: Barker, Christopher A., Bishop, Andrew J., Chang, Maria, Beal, Kathryn, Chan, Timothy A.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2013
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4667941/
https://ncbi.nlm.nih.gov/pubmed/23523186
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ijrobp.2013.02.012
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