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Glucose Evokes Rapid Ca(2+) and Cyclic AMP Signals by Activating the Cell-Surface Glucose-Sensing Receptor in Pancreatic β-Cells

Glucose is a primary stimulator of insulin secretion in pancreatic β-cells. High concentration of glucose has been thought to exert its action solely through its metabolism. In this regard, we have recently reported that glucose also activates a cell-surface glucose-sensing receptor and facilitates...

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Publicat a:PLoS One
Autors principals: Nakagawa, Yuko, Nagasawa, Masahiro, Medina, Johan, Kojima, Itaru
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2015
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4667910/
https://ncbi.nlm.nih.gov/pubmed/26630567
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0144053
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