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Sweet Taste Receptor Expressed in Pancreatic β-Cells Activates the Calcium and Cyclic AMP Signaling Systems and Stimulates Insulin Secretion

BACKGROUND: Sweet taste receptor is expressed in the taste buds and enteroendocrine cells acting as a sugar sensor. We investigated the expression and function of the sweet taste receptor in MIN6 cells and mouse islets. METHODOLOGY/PRINCIPAL FINDINGS: The expression of the sweet taste receptor was d...

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Detalhes bibliográficos
Main Authors: Nakagawa, Yuko, Nagasawa, Masahiro, Yamada, Satoko, Hara, Akemi, Mogami, Hideo, Nikolaev, Viacheslav O., Lohse, Martin J., Shigemura, Noriatsu, Ninomiya, Yuzo, Kojima, Itaru
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2009
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2663034/
https://ncbi.nlm.nih.gov/pubmed/19352508
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0005106
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