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Non-Specific Blocking of miR-17-5p Guide Strand in Triple Negative Breast Cancer Cells by Amplifying Passenger Strand Activity

Conventional wisdom holds that only one of the two strands in a micro ribonucleic acid (miRNA) precursor duplex is selected as the active miRNA guide strand. The complementary miRNA passenger strand, however, is thought to be inactive. High levels of the oncogenic miRNA (oncomiR) guide strand called...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Jin, Yuan-Yuan, Andrade, Jade, Wickstrom, Eric
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4667903/
https://ncbi.nlm.nih.gov/pubmed/26629823
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0142574
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