Both mature miR-17-5p and passenger strand miR-17-3p target TIMP3 and induce prostate tumor growth and invasion

MicroRNAs (miRNA) precursor (pre-miRNA) molecules can be processed to release a miRNA/miRNA* duplex. In the canonical model of miRNA biogenesis, one strand of the duplex is thought to be the biologically active miRNA, whereas the other strand is thought to be inactive and degraded as a carrier or pa...

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Detalhes bibliográficos
Main Authors: Yang, Xiangling, Du, William W., Li, Haoran, Liu, Fengqiong, Khorshidi, Anna, Rutnam, Zina Jeyapalan, Yang, Burton B.
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2013
Assuntos:
Gene Regulation, Chromatin and Epigenetics
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3834805/
https://ncbi.nlm.nih.gov/pubmed/23990326
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkt680
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