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Both mature miR-17-5p and passenger strand miR-17-3p target TIMP3 and induce prostate tumor growth and invasion

MicroRNAs (miRNA) precursor (pre-miRNA) molecules can be processed to release a miRNA/miRNA* duplex. In the canonical model of miRNA biogenesis, one strand of the duplex is thought to be the biologically active miRNA, whereas the other strand is thought to be inactive and degraded as a carrier or pa...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Yang, Xiangling, Du, William W., Li, Haoran, Liu, Fengqiong, Khorshidi, Anna, Rutnam, Zina Jeyapalan, Yang, Burton B.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Oxford University Press 2013
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3834805/
https://ncbi.nlm.nih.gov/pubmed/23990326
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkt680
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