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Non-Specific Blocking of miR-17-5p Guide Strand in Triple Negative Breast Cancer Cells by Amplifying Passenger Strand Activity

Conventional wisdom holds that only one of the two strands in a micro ribonucleic acid (miRNA) precursor duplex is selected as the active miRNA guide strand. The complementary miRNA passenger strand, however, is thought to be inactive. High levels of the oncogenic miRNA (oncomiR) guide strand called...

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Pubblicato in:PLoS One
Autori principali: Jin, Yuan-Yuan, Andrade, Jade, Wickstrom, Eric
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2015
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4667903/
https://ncbi.nlm.nih.gov/pubmed/26629823
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0142574
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