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Non-Specific Blocking of miR-17-5p Guide Strand in Triple Negative Breast Cancer Cells by Amplifying Passenger Strand Activity

Conventional wisdom holds that only one of the two strands in a micro ribonucleic acid (miRNA) precursor duplex is selected as the active miRNA guide strand. The complementary miRNA passenger strand, however, is thought to be inactive. High levels of the oncogenic miRNA (oncomiR) guide strand called...

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Publicat a:PLoS One
Autors principals: Jin, Yuan-Yuan, Andrade, Jade, Wickstrom, Eric
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2015
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4667903/
https://ncbi.nlm.nih.gov/pubmed/26629823
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0142574
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