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Clonal Analysis of a Human Antibody Response: II. Sequences of the V(H) Genes of Human IgM, IgG, and IgA to Rabies Virus Reveal Preferential Utilization of V(H)III Segments and Somatic Hypermutation()
The construction of mAb-producing cell lines has been instrumental in dissecting the fine specificities and genetic makeup of murine antibodies to exogenous and self Ag. The analysis of the genetic composition of human antibody responses has been hampered by the difficulty in generating human mAb of...
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| Veröffentlicht in: | J Immunol |
|---|---|
| Hauptverfasser: | , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
1993
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4667541/ https://ncbi.nlm.nih.gov/pubmed/8432980 |
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