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Complete sequence of the genes encoding the V(H) and V(L) regions of low- and high-affinity monoclonal IgM and lgA1 rheumatoid factors produced by CD5(+) B cells from a rheumatoid arthritis patient
We have characterized the V(H) and V(L) genes of three low-affinity polyreactive and two high-affinlty monoreactive IgM and lgA1 rheumatoid factor (RF) mAb generated using circulating CD5(+) B cells from a single rheumatoid arthritis patient. We found that four and one RF mAb utilized genes of the V...
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| Pubblicato in: | Int Immunol |
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| Autori principali: | , , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
1991
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4632984/ https://ncbi.nlm.nih.gov/pubmed/1718404 |
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