Complete sequence of the genes encoding the V(H) and V(L) regions of low- and high-affinity monoclonal IgM and lgA1 rheumatoid factors produced by CD5(+) B cells from a rheumatoid arthritis patient

We have characterized the V(H) and V(L) genes of three low-affinity polyreactive and two high-affinlty monoreactive IgM and lgA1 rheumatoid factor (RF) mAb generated using circulating CD5(+) B cells from a single rheumatoid arthritis patient. We found that four and one RF mAb utilized genes of the V...

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Publicado no:Int Immunol
Main Authors: Harindranath, Nagaradona, Goldfarb, Inna S., Ikematsu, Hideyuki, Burastero, Samuele E., Wilder, Ronald L., Notkins, Abner L., Casali, Paolo
Formato: Artigo
Idioma:Inglês
Publicado em: 1991
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4632984/
https://ncbi.nlm.nih.gov/pubmed/1718404
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