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Structure of the V(H) and V(L) Segments of Mono reactive and Polyreactive IgA Autoantibodies to DNA in Patients with Systemic Lupus Erythematosus()
Anti-DNA IgA autoantibodies play an important immunopathologic role in SLE patients. To analyze the cellular origin and the V(H) and V(L) structure of anti-DNA IgA autoantibodies, we generated five IgA1 mAbs to DNA using B lymphocytes from three SLE patients. Two mAbs bound to ssDNA only and one to...
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Pubblicato in: | J Immunol |
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Autori principali: | , , , |
Natura: | Artigo |
Lingua: | Inglês |
Pubblicazione: |
1994
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Soggetti: | |
Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4631053/ https://ncbi.nlm.nih.gov/pubmed/8144908 |
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