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Structure of the V(H) and V(L) Segments of Mono reactive and Polyreactive IgA Autoantibodies to DNA in Patients with Systemic Lupus Erythematosus()

Anti-DNA IgA autoantibodies play an important immunopathologic role in SLE patients. To analyze the cellular origin and the V(H) and V(L) structure of anti-DNA IgA autoantibodies, we generated five IgA1 mAbs to DNA using B lymphocytes from three SLE patients. Two mAbs bound to ssDNA only and one to...

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Detalhes bibliográficos
Publicado no:J Immunol
Main Authors: Kasaian, Marion T., Ikematsu, Hideyuki, Balow, James E., Casali, Paolo
Formato: Artigo
Idioma:Inglês
Publicado em: 1994
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4631053/
https://ncbi.nlm.nih.gov/pubmed/8144908
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