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Two-Variance-Component Model Improves Genetic Prediction in Family Datasets

Genetic prediction based on either identity by state (IBS) sharing or pedigree information has been investigated extensively with best linear unbiased prediction (BLUP) methods. Such methods were pioneered in plant and animal-breeding literature and have since been applied to predict human traits, w...

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Bibliografske podrobnosti
izdano v:Am J Hum Genet
Main Authors: Tucker, George, Loh, Po-Ru, MacLeod, Iona M., Hayes, Ben J., Goddard, Michael E., Berger, Bonnie, Price, Alkes L.
Format: Artigo
Jezik:Inglês
Izdano: Elsevier 2015
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4667134/
https://ncbi.nlm.nih.gov/pubmed/26544803
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajhg.2015.10.002
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